Today, we have for you the โGluten Show.โ
But this isnโt your average gluten showโฆ No. We are kicking it Enterprise style, and weโve tracked down one of the worldโs leading authorities on the topic, Dr. Thomas OโBryan.
Dr. Thomas OโBryan is an internationally recognized speaker, specializing in gluten sensitivity and the celiac disease. He is the Sherlock Holmes for chronic disease and metabolic disorders. He holds a teaching faculty position with the Institute of Functional Medicine and the National University of Life Sciences.
Dr. O โBryan is passionate about teaching the many manifestations of gluten sensitivity and zodiac disease, as they all occur inside and outside the intestine.
Tune in to find out facts about gluten, how it affects your health, whether you should go on a gluten-free diet, and so much more!
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Transcript From Gluten Podcast
Due to the nature of transcriptions, we cannot guarantee accuracy, spelling or grammar. We provide the transcription as a way to skim through the content and as revision notes.ย
This transcription will contain errors.
Mark: This podcast is brought to you by maximusmark.com. Hey folks, welcome to the show that punches you in the face with informationโฆ but in a good way. Itโs Maximus Mark. And today I have for you the โGluten Show.โย But this isnโt your average gluten showโฆ no. We are kicking it Maximus mark style and Iโve tracked down one of the worldโs leading authorities on the topic, Dr. Thomas OโBryan.ย
Dr. Thomas OโBryan is an internationally recognized speaker, specializing in gluten sensitivity and the celiac disease. He is the Sherlock Holmes for chronic disease and metabolic disorders. He holds a teaching faculty position with the Institute of Functional Medicine and the national University of Live Sciences.
Dr. O โBryan is passionate about teaching the many manifestations of gluten sensitivity and zodiac disease, as they all occur inside and outside the intestines. You can learn more about Dr. OโBryan by visiting www.thedr.com.
So with all that said, letโs welcome Dr. OโBryan to the show.
Hi Tom, itโs Mark. How are you doing?
Dr. OโBryan: Hi Mark, very well, thanks. How are you today?
Mark: Iโm very good. Absolute pleasure to speak to you today and really looking forward to this call. Iโve learned a lot of your stuff, and listened to a lot of your videos. I went in your website and downloaded a lot of your podcasts. And itโs really great information, really great what youโre doing.
Dr. OโBryan: Thank you.
Mark: Really appreciating you coming on today and talk about it.
Dr. OโBryan: You bet, happy to do it.
Mark: Thanks for that.
So, let me ask you. How did you become a leading expert in the field of gluten?
Dr. OโBryan: Well, I was in a seminar in 2001 with Dr. David Perrymotor, neurologist from Naples and he was talking about a study that adjusted publish in the journals of neurology.ย
That talked about 10 people with unrelenting migraines. And their migraines were so bad that they were unable to work. And the average was 8 years that they had been out of work, on workmanโs compensation. And I youโre on workmanโs compensation, youโre not a malingerer. These are people who are truly suffering.ย
And somehow, what came up for me was, I wondered what itโs like to live in that house, what itโs like for the children of that family when dadโs got a headache. โShh, shh, shh, quiet, quiet dadโs got a headache.โย
How is it growing up in a house like that and the house suppressed like the children being suppressed in that family where they hadnโt had an income in eight years? Living off retirement funds, and disability and whatever they could get.ย
So I ordered that paper because I was caught by the concept. And I read the paper. Turned out that seven out of ten of those migraine patients were sensitive to gluten. They did not have celiac disease, they were sensitive to gluten.ย
And the doctor took the gluten off their diets and the seven out of ten never had a migraine again and two out of ten had partial relief, and the other one refused the diet.ย
I said that wrong. Ten out of ten has sensitivity to gluten. Seven never had a headache again on the gluten-free diet, two had a partial relief out on a gluten-free diet, and the tenth one refused to diet.ย
Mark: Wowโฆ
Dr. OโBryan: So that really caught me. So I looked at the references at the back of the paper and ordered those papers and started reading them, and Iโve read hundreds of articles now on this.
Mark: So yeah, ten out of ten. So yeah, I guess letโs start with the most obvious because when I tell all my clients and my listeners to obviously avoid gluten, you know. But the most questions I get from most people introduced to gluten isโฆ What exactly is it and what theories has it founded?
Dr. OโBryan: Yeah, good, good, good question. Gluten is the protein in most grains.ย Itโs a family of proteins. Rice has gluten, corn has glutenโฆ But there is a toxic family of glutens that are found in wheat, rye, and barley.ย
So anything that is made from wheat, rye, and barley will have some of this protein in it and if youโre toxic to that, your body thinks that youโre eating a poison. And when youโre eating something thatโs dangerous to you, the immune system comes into action to go after it. And that what happens to celiac disease or with gluten sensitivity. In general, the immune system goes after these proteins of glutens to destroy them.ย
So thatโs not a problem at all. But if youโre having toast for breakfast, and a sandwich for lunch, and pasta for dinner, and the next day youโre having toast for breakfast and a sandwich for lunch, and lasagna for dinner, and the next day youโre having toast for breakfast, and a blueberry muffin for lunch, and croutons on your salad for dinnerโฆ I think you get my point that we keep eating more and more gluten.ย
I guess the easiest way to say is that thereโs a collateral damage that occurs. And once collateral damage occurs, from all the immune activity trying to protect you from a poison, once the collateral damage begins to occur, then it has a life of itโs own.ย
This is how you develop other autoimmune diseases with gluten sensitivity. And we know that autoimmune diseases are one of the primary causes of morbidity and mortality. That means getting sick or dying in the world today and we know that autoimmune diseases are ten times more common if you have gluten sensitivity.ย
So the number one cause of death in the world, of the highly industrialized world, is ten times more common if you have sensitivity to gluten.ย Gluten is the gasoline on the fire for most people. There maybe others also, but gluten is the primary one.
Mark: One of the tings I heard you mention in the past interviews and podcasts is that 70% of celiacs goes undiagnosed, because thereโs no symptoms in the guide. Is that correct?
Dr. OโBryan: Actually, thatโs close. Thatโs one out of eight. For every one that has symptoms in their intestines, there are eight that donโt.ย
Theyโve got brain symptoms, or joints symptoms, or skin symptoms, theyโve got psoriasis, rheumatoid arthritis or recurrent ear infection or migraines, or tension deficit, or kidney disease, or muscle cramps, or anemia, or miscarriagesโฆ the list goes on and on and on.ย
Mark: So miscarriages are also linked to gluten intolerance, is that correct?
Dr. OโBryan: Oh yes. I actually published a paper on this in the Journal of x of Gastrology in 2009 called Reproductive Disorders and Celiac Disease. And gluten sensitivity, celiac disease, is one of the most common causes of unexplained miscarriages.ย
Mark: Wowโฆ Thatโsโฆ I didnโt know that one. So gluten you spoke before, about your immune system obviously on alarm. So what are the things I sometimes get a little bit confused with isโฆ Does gluten cause an inflammation response, or does it cause an immune response? And why is that significant?
Dr. OโBryan: Good. The inflammation is the mechanism of all the generative diseases. As far as I know, the generative disease, at the cellular level, is always in the inflammatory state, always.ย
When you eat a food that youโre allergic to, your immune system gets called into action. And what it does is it goes after that food to attack it.ย It attacks that food, and it does so by producing cytokines, are chemical bullets, if you will. That will cause that inflammation that kills the cells, or it destroys that protein.ย
You also make antibodies against that food. First, itโs the natural immune system, called the innate immune system, and you make these interleukins that produce cytokines and try to destroy it. And when they canโt do their job any longer, they may have to call in the reserves. And the reserves are the antibodies.ย
And the antibodies come in, and the antibodies attack the substance and try to destroy it also.ย Itโs always an inflammatory mechanism by which the invaderโฆ itโs always an inflammatory response that kills the invader.ย
Mark: Right, gluten causes the inflammatory response. And then, is there ant immune response to that?
Dr. OโBryan: Gluten causes the inflammation response. What happens is that gluten causes mechanisms in the intestines, itโs called the intestinal permeability or the slang term for this is โleaky gut.โ Thereโs leaky gut occurs within 36 hours of eating gluten. And leaky gut occurs because the immune system is attacking these gluten protein molecules and trying to destroy them. And it does so by producing this inflammation, these cytokines that causes inflammation that destroys the cell. When you have recurrent episodes, this minor amount of inflammation is almost undetectable until youโre getting exposed to the same day after day after day after dayโฆ now it becomes an inflammatory state. And now youโve got measurable amounts of inflammation and all the tissue damage that occurs from that.
Mark: Alrighty. So itโs my understanding that if you have any type of gluten sensitivity, you basically canโt have a period in your diet. Why is that?
Dr. OโBryan: Well the rule is you canโt be a little pregnant. And, you canโt have a little gluten. And the reason for that is that the mechanism by which the antibody are produced to the gluten proteins of wheat, barley and rye, is the same mechanism by which the antibody is produced to measles or any other of the vaccines that weโve received in our life.ย
So what happens with the measles vaccine, as an example, they give you an injection of the bug measles. Your brain says, โthis is not good for me.โย
And there are generals in you immune system. Army, Air Force, Navyโฆ generalsโฆ And the brain says, โYou general, you know our General Gluten, take care of this.โย
General Gluten produces an assembly line that starts making soldiers.ย Those soldiers are called antibodies.ย And those soldiers are trained to go after gluten. Thatโs all they do, or go after measles. All they do is go after measles.ย
Now those soldiers in your bloodstream; they go around shooting all the measles bugs that you were injected with. And when all the measles bugs are destroyed; General Measles, whoโs watching all this will say, โOkay, turn off the assembly line. We donโt need more measles antibodies here right now.ย You shouldnโt have any measles antibodies in your bloodstream right now unless youโre exposed to measles. You shouldnโt have any.โ
But General Measles is now vigilant the rest of his life, the rest of his life. His main job, if measles ever come back, General Measles doesnโt have to build an assembly line again.ย He just needs to flip the switch and turn it back on. And the antibodies are out very very quickly.
Thatโs why if you go to Africa to visit, you need vaccinations months ahead of time for all the strange diseasesโฆ dengue fever, yellow fever, all of the diseases that you might be at risk of contracting in Africa. You need vaccinations ahead of time.ย
But if you are going to visit 5 years later, you just need a booster shot 2 weeks before you go.ย Because you just need to wake up the general again to start making the antibodies.
Mark: So Iโve heard in the past, a lot of people talk about that it takes 90 days, it is basically a 90 day rule that it takes the body to reset and for the antibodies to go down. Can you talk a little bit more about this?
Dr. OโBryan: The lifespan of antibodies is anywhere between four to six weeksโฆ perhaps a little longer, maybe up to eight weeks.ย
So one exposure to glutenโฆ General Gluten, get s turned on, he flips the switch, the antibodies are produced within 14 days, and they are around four to six weeks, for to eight weeksโฆ somewhere around that category from one exposure.
So if youโre having gluten everyday, the mechanism just stays, the assembly line is up and running, working three shiftsโฆ three 8-hours a day.ย
Mark: So is thereโฆ I guess weโve said before you canโt be a little pregnantโฆ I remember you telling a story about as much a one milligram, not even a full gram of gluten will cause response. If basically, someone goes to a restaurant, and someoneโs making pasta, and they use the same spoon to make the steak, that can actually cause a gluten response. Is that right?ย
Dr. OโBryan: Thatโs exactly right. In senses of individuals, thatโs all it takes.ย The codecs limit is 20 parts per million. So imagine a million pinheads sitting on your desktopsโฆ a million pinheads. Then imagine how many 20 of those are.ย Thatโs how much gluten it takes to activate general gluten.ย
Mark: So not a lot at all. Just a little gluten will cause a response. So let me ask you this. People have been taking about oatmeal and having oats in the morning, and porridge ant these types of things. But to my understanding, these are made in the same place as other wheat products. So in your opinion, is that to say we should avoid rice or oatmeal?
Dr. OโBryan: Well, they are different grains. Oatsโฆ itโs been published that when oats grow out of the ground, thereโs no toxic gluten in them.ย When you buy oats off the supermarket shelf, thereโs gluten in them. And its contamination is cross-contamination when they harvest the oats from the field, they fill in the truck to drive to the manufacturing station, and itโs contaminated with wheat last week when they donโt clean the truck. Or in the same facility with those in the air, on the assembly line, something like that.
Here in the US there are few companies, they are very proud to put on their label โgluten freeโ oatmeal ofย โgluten freeโ oats. And they go out of the way, and they test their batches that they are completely gluten-free.ย
So in general, itโs not safe to eat oatmeal out in the restaurant. In general, if youโre celiac, itโs not safe because when theyโve looked at different brands of oatmeal, theyโre all contaminated. Even those from the oats only facility, like McCannโs, which is a famous oats here in the US that comes from Ireland. Theyโre grown and theyโre packaged in Ireland, which is an oats-only facility. But two put of the four samples that they looked at have levels of gluten above the toxic limit.ย
So if you eat oats, and we recommend our patients to eat oatmeal, itโs okay. And if you donโt eat it the way we see they should, then we take oats out. But you just have to make sure that the oats you are using are gluten-free oats.ย
Mark: Right, and that is normally advertised on the packet.
Dr. OโBryan: Thatโs correct.
Mark: Cool. So let me ask you this. So in case someone turns around and get a gluten test, and comes back they are not intolerant, they can actually have gluten. Would you advise to keep having gluten?
Dr. OโBryan: Well, thereโs a couple of different level to that answer. The first one is body language never lies, it never lies. And many of us speak a second language, perhaps Spanish or French or Italian, many English-speaking people speak a second language.ย
How many speak body? Most of us donโt speak body at all. We donโt understand the language. We donโt listen to it. If something is going on, we take an aspirin and get rid of the headache. But if we get headaches two or three times a week, we take aspirin two or three times a week, and not worry about it.ย
Itโs like going under the dashboard of a car, and a hot leg comes on, and so you go under the dashboard, and you look for a wire going under a hot leg and you cut the wire. And you donโt see the hot leg anymore, and you keep driving your car.ย
We donโt speak body.ย And we should learn to speak body. From that context, the best test in the world, stop eating gluten. Completely stop from two to three weeks.ย
Notice what happens. If you feel better, and then you go back and start eating gluten again, and then you start heading to feeling not better, then your body is telling you, โI donโt feel better when Iโm taking this, when you put this thing in me.โ So thatโs the first answer.
The second answer is that the tests are notoriously inaccurate. Itโs called total villous atrophy. That meansโฆ the inside of your intestineโฆ itโs a tubeโฆ your intestines are tubes going through your abdomen. ย
The inside of the intestine is lined with shagged carpeting.ย And each shag absorbs different nutrients.ย The shag overhears calcium, the shag overhears magnesium. This one is oils, this one is good fats, this one is proteins, all the shags absorbs different nutrients.ย
Celiac disease, which is gluten sensitivity effect in the gut. Celiac disease works the shag. So you donโt have shag carpeting anymore, you have beriberi.ย And if you have beriberi carpeting, you donโt absorb calcium. You get osteoporosis; itโs not rocket science.ย
Thatโs why the analyst of the internal medicine, they say every osteoporotic patient needs to be checked for celiac disease. Celiac disease could be the cause of their osteoporosis.ย
So I say to the doctors, when they show me a test. I say โDoctors, when the analyst of the internal medicine say every osteoporotic patient needs to be tested for celiac disease, because celiac could be the causes of osteoporosis, which one are you not gonna check?โ Then thereโs silence in the room. So the tests are notoriously inaccurate because, we go back up, the tests are on the money, completely accurate. Right on the money, very high degree of sensitivity and specificityโฆ 96, 98, 100%. Very, very accurate if you have total villous atrophy. ย
If your shags are ward down completely, youโve got beriberi. The blood tests are very accurate. If you only got partial wearing down, or if you just got the inflammation, nothing worn down yetโฆ the blood tests are wrong up to seven out of ten times. So the blood tests are very accurate on all the studies saying how accurate they are for celiac disease. But celiac disease requires the shags to be worn down completely.ย Total villous atrophy.ย
I call this the conundrum, gluten sensitivity. This is why so many people get blood test, they come back negative, but they stop in a week, they feel better. If the blood test says negative, I guess I can eat wheat.ย
So theyโre not listening to body language. Theyโre listening at a piece of paper that was wrong.ย
New tests have just come out here in the US, the last 3 monthsโฆ the reason the tests are wrong, and theyโre not sensitive enoughโฆ One of the reasons is becauseโฆ see, gluten is a protein. And the protein molecule is made up of hundreds of amino acids. Theyโre the building blocks, if you will. Theyโre the bricks that make up the wall of the protein gluten. ย
Digestion is removing the mortar from in between the bricks, so each brick comes off. Good digestion breaks down your protein into single amino acid. They go right through the shags into the bloodstream.ย
Thatโs normal, thatโs how itโs supposed to occur.ย
But when you have gluten sensitivity, itโs like someone took a sledgehammer to the wall. And broke the wall into big clumps, 17 bricks, 33 bricks, 18 bricks, 44 bricks. These big clumps of bricks still have the mortar on them. Thatโs when you have gluten sensitivity and you donโt break down your food very well.
Those big clumps go into the bloodstream, and the immune system goes into the bloodstream to fight it. And here comes the whole cascaded effects.ย
The blood test looks at one clump. They look at 30-brick clump. Itโs called 33-mer peptide of gluten, called alpha gliadin. All of the tests look for the same thing, alpha gliadin. Thatโs all they look for. But we know that there are over 60 peptides of gluten clumps of the brick wall. Sixty different ones that the gluten will react to.ย Why are we only testing one? Which is my question.ย
A laboratory opened up just three months ago. And theyโre testing the top ten peptides of gluten.ย And now we arenโt getting the false negative anymore. And people are getting exactly what they got and there is an accurate test. The lab is called Cyrex, cyrexlabs.com. Youโre listening and you can go there and they can find the doctor in their area, that has an account with Cyrex and order the test to be done.ย
And if they donโt have someone in their area then Cyrex will tell you where the closest one is.ย
Mark: Do you do it internationally?
Dr. OโBryan: Not yet. Soon, but not yet. Iโve been speaking Mexico, Canada, and London, Brazilโฆ and theyโre all very, very interested and they really want this test because it makes perfect sense. So we hope within the next year.
I was actually speaking with someone last week from New Zealand, who would like to bring in the test over to New Zealand and Australia.
Mark: Thatโs great.
Dr. OโBryan: Iโm sure next year, theyโll be there.
Mark: So, I guess itโs long distance listening I from Australia. What tests can we ask for? Or is it really learning to speak body?
Dr. OโBryan: Well, the only tests that are available are looking for, if you say you want a test for gluten sensitivity, what they check is gliadin. Because 50% of studies say 50% of celiacs will have antibodies to gliadin, but the rest of them donโt. And they say, โWell, thatโs not a good test then.โ Theyโll say itโs not a sensitive test. Well, thatโs true.ย
Thatโs because these people are reacting to different peptide. The other 50% reacting to gliadin are not reacting to gluten morphine, or glutinents. Or 17 mer or 13 or 11 mer. Theyโre not reacting to the 33 mer. So the first test thatโs done, such as I believe the only test done in Australia is for the 33 mer gliadin peptide and the other is transglutaminase.ย
Transglutaminase is an enzyme that is in the Saran wrap that covers the shags. Do you have Saran wrap over there?
Mark: Ah, I think we call itย that.
Dr. OโBryan: Ah, right just like the cling wrap. So transglutaminase is an enzyme inside the cling wrap. And if youโre buying the extra antibodies for transglutaminase, you destroy the transglutaminase, you destroy the cling wrap. And you get the leaky gut intestinal permeability. Itโs such a major problem.
So, the only tests that are over there are gliadin and transglutaminase as far as I know. And if youโre positive there, youโre really positive. If youโre not positive there, it doesnโt mean that youโre negative for celiac disease. It just means that that test doesnโt identify it.ย
So the most sensitive thing that you can do is to get a gluten-free and dairy free diet for three weeks. No dairy of any type and no gluten of any type for three weeks.
The enzyme that breaks down the sugar molecules in dairy, the enzyme is called lactase. Lactase is produced in the single cell outside lining in the shags of the epithelium. So when your shags are inflamed, or when your shags wear down, you donโt produce the enzymes to break down the protein molecules in dairy. And you feel more inflammation because of the poorly digested protein molecules of dairy. In papers where theyโve looked at this, they put people on a gluten free diet and check to see if they were making their enzymes to dairy. And six months, the answer was no.ย
It took a year, a year on the gluten-free diet. And some of these people, not all of them, some of these people started making their enzymes again to break down dairy.
Mark: Right
ย
Dr. OโBryan: When you eat dairy, if you have celiac disease or gluten sensitivityโฆ when you eat dairy, your body still thinks youโre eating gluten. Itโs called the cross-reactive reaction.ย
Mark: And I think youโve talked about caffeine, getting rid of caffeine except green tea. What is their reaction in caffeine?
Dr. OโBryan: Well, thereโs two levels to answer that question. First, is part of the protocol to heal the gutโฆ getting caffeine out of there is important because it will cause inflammation in the intestine and youโre trying to heal the damages there.ย
Another level to answer that question is that caffeine is a cross-reactive food. Excuse me, coffeeโฆ Coffee is a cross-reactive food. So if youโre sensitive to coffee, not everyone isโฆ But if youโre sensitive to coffee, your body thinks youโre sensitive to gluten and you keep getting the same damages as if youโre eating gluten.ย
Mark: Right, so how do you find out if youโre sensitive to coffee?
Dr. OโBryan: Well the tests fro Cyrex labs, they have a test called cross-reactive foods. This lab is set up specifically to identify gluten sensitivity and identify the complications that occur from gluten sensitivity.ย
This lab, I do believe is going to change the face of medicine in terms of tests because the doctors will have much more ammunition now to show to the patient why they feel the way they do which will instill more compliance. The patients will follow along with the recommendation and then they get better.ย
Mark: With that said, let me ask you this question. What do you think of theโฆ I guess the compliancy of the doctor to implement lifestyle changes to the patient? Because I donโt knowโฆ the western medicine does things a little bit to the other side, thatโs the prescribed pills rather than look at the patientโs health.ย
Dr. OโBryan: Well thatโs true. Thatโs because thatโs how they were trained. Unfortunately, the educational system for the medical doctor is not what it teaches them about health care. Theyโre taught about crisis care.ย And when thereโs a crisis, hereโs the medication to use.ย And we call that acute care, and itโs of great value.ย
And almost all of the medication that have been approved in the US, Iโm not sure if they have this in Australiaโฆ But certainly in US, all of the medications have been approved for short-term use.ย They were not designed to be taken long-term.ย And the resultโฆ when you take them long-termโฆ nobody knows how things are gonna be. And people get surprised with some of the complications that occur.ย
Unfortunately, our medical doctors are not trained in health care. Theyโre trained in crisis care. So we need to re-educate them, and there are many, many schools now that are doing that.ย
Functional medicine is beginning to take a more primary role in the education of medical doctors which is just fabulous. With that said, weโll have the best of both worlds.
Mark: I heard a parent said the other date, it was at a debate that we were havingโฆ Obviously I did not want to take part in it because my opinion was a little bit too outspoken. One of the parents said that you should get your child adapted to gluten. So you give your child gluten at an early age and they will adapt to it. Can you explain perhaps the problem with this approach?
Dr. OโBryan: There are some research papers that have identified in the group of high risk infantsโฆ meaning their parents, one or twoโฆ their parents have celiac disease. In that group of high risk infantsโฆ if you introduce minute amount of gluten to them, between three and six months of ageโฆ not before, and not afterโฆ but between three to six months of ageโฆ it seems to have a beneficial effect in strengthening their resilience being exposed to these foods that they are likely genetically sensitive to.
So, what is minute amounts of gluten? Well, a child between three to six months of age doesnโt have teeth yet. So theyโre still breast-feeding.ย I believe we recommend our patients consider, that if when your child got teeth, its time to give them food.ย
Until then, thereโs one food that is ideal for themโฆ so a child breast-feeding between three and six months. So if the mother has just a little bit of gluten, half a crackerโฆ half a cracker is just all it takes. And if she chews it very well and take some digestive enzymes, those protein molecules will get into the blood going to the infant.
And youโre exposing the infant to minute amounts, pre-digested, poorly but pre-digested gluten, minute amounts of itโฆ and it appears to be able stimulate the immune system to desensitize that baby to gluten. It appears to be that way. Itโs not a recommendation from the American College of Pediatrics or any other medical education group that Iโm aware of. But there is some talk about it and there had been some papers written about it.ย
Mark: Okay, and if the child is letโs say, two or three years old, or four years old, is that too late in a sense?
Dr. OโBryan: Well, if the child has not had gluten, and they are two to four years old, theyโre well on the way to being extremely healthy and strong. As the numbers keep getting out above the frequency of gluten sensitivity it keeps getting more and more shocking.ย
If they are between two to four years of age, and the parent wants to know what to do here, if thereโs a family history of celiac disease, or gluten sensitivityโฆ the first thing I will do is recommend the genetic test. If the child is carrying the gene, donโt expose them to gluten.ย If you can keep gluten out of their life, theyโre gonna do so much better. If they got the gene, and thereโs family history of celiac disease.ย
If the child does not have the gene, then you can do, if you want I guessโฆ you can do a small amount, which would be a third of a cracker. I just give a small amount, you have to chew it really well and do that three, four days a week, for a couple of weeks, then do the blood test. Looking for the antibodies to multiple peptides of gluten.ย Not just to the gliadin, but multiple peptides. And hopefully, the test will be over there before too long so that Australians will have access to it also.ย
Mark: Yeah, so a functional medicineโฆ I guess tip that I was given, was blue eyes, blond hair are actually more at risk of having intolerance to gluten. Is it true?
Dr. OโBryan: Well there is a tendency for certain ethnic groups to have more tendencies towards it, more vulnerability towards it, and blond haired, blue-eyed is one of those groups.
The Mediterranean cultures Greeks, Italians, French, North Africans, and the Norwegians, the Nordic cultures also have a high sensitivity, vulnerability as those Asconasy Jewish people. And Iโm not sure that thereโs been a differentiation between Australia, New Zealand and the US, I think they all fall into the same category.ย
Mark: Right, okay. One of my teachers taught me that gluten affects the brain. And basically builds plaque block on it like a tooth. Can you explain this?
Dr. OโBryan: The most common system of the body thatโs affected by gluten is brain, not the gut. The most common system is the brain. And can cause whatโs called the small vessel disease, where some of the blood vessels plaque up. They get hardened. Not inside the center of the blood vessel, but at the walls of the blood vessel, it get hardened. Other areas of the brain, it will cause white matter lesions. In the brain where part of the brain tissue called white matter, starts to calcify. It just hardens up. And there are actually some papers on reversing some lesions in the brain when you put the person on a gluten-free diet.ย
Mark: So would gluten be linked to things like Alzheimerโs?
Dr. OโBryan: Yes it has actually. The Journal of Gastrology in 2008, they published a paper to people. They checked the amount of the Alzheimerโs facility after they put them in the gluten free diet. Because they came back, they were functional again. ย
And itโll affect any tissue of the body, any tissue of the body. Iโm sorry, let me sat it a little different โฆ itโll affect any tissue of the body. When I say it like that, when I repeat it three times four timesโฆ then someone asks me, โWell, can it affect my liver?โ Iโll say itโll affect any tissue of your body. Your thyroid, your skin, your nose, your eyes, multiple sclerosis, rheumatoid arthritis, colitis, the list goes on and on and on. There are over 19,000 papers now published in the medical literature on gluten sensitivity and celiac disease.ย
Mark: So it can even affect tings like muscle test, and muscle poles, things like that?
Dr. OโBryan: Oh my goodness, any tissue in the body. But especially that, you bet. The athletes, they have a lot of fibrosis. We found out that when they go on a gluten-free diet, their muscles soften up. Theyโre much more pliable, which allows them to be more elastic, it means they get much more power out of the every contraction of the muscle.ย
Mark: I just want to ask you some facebook questions. Some of these we kind of already answered, but jus to reiterate, one of the facebook questions I got is, โWhat about rice?โ
Dr. OโBryan: Rice does not have toxic gluten peptides in it. Rice is rice. Some people are allergic to rice, some people are allergic to tomatoes, and some people are allergic to artichoke. You could be sensitive to anything.
Rice is on the cross-reactive food panel because a lot of people eat rice on a gluten-free diet, and thatโs not a problem. But remember, weโre not supposed to be eating the same food everyday. The only thing weโre supposed to have the same is water. Everything else is supposed to come through the seasons. Solid diets will vary due to seasons.ย
So once you eat rice, five, six, seven days a week, you easily can build up a sensitivity to rice.ย
Mark: Yes, for sure. What can you say about the statement that gluten is nothing to be worried about if youโre not a celiac?ย
Dr. OโBryan: If itโs the general public, they just donโt know and itโs not their fault. If heโs in the same position, heโs got his head in the dark places. There are hundreds of hundreds of articles about gluten sensitivity outside the gut causing ataxia. Ataxia is when you get the cerebellum area of your brain destroyed and you canโt walk very well anymore. And thereโs noting wrong with your legs. Itโs that you donโt have control in your brain.ย And thatโs from gluten.
As a matter of fact, thatโs the main cause of idiopathic ataxia. Idiopathic means we donโt know where the problem comes from. When someoneโs got ataxia, and itโs idiopathic, gluten sensitivity is the main culprit. Itโs published in the literature. Gluten sensitivity will cause chronic fatigue. It will cause fibro fibromyalgia myotion, it will cause major depressant disorder.ย Not minor depression where little medication helps or moderate where they can take a couple of drugsโฆ Major depression which is very, very difficult to treat. These people just donโt function very well. And they are staying alive on their medication.
Gluten sensitivity cause major depressant disorder, by itself without celiac disease. So that person, if itโs a healthcare practitioner, they need to read the literature a little more before making statements like that.
Mark: So I guess, the other sets of questions weโre gonna askโฆ weโve kind of answered that alreadyโฆ
ย Why should the average person take out gluten from their dietโฆ โcause as youโve saidโฆ it can lead to all these other of problems and it affects all the other tissues in the body.
Dr. OโBryan: What youโll find out in the next year or so in the papers that are published is that seven out of ten that were checked have gluten sensitivity. You just have to have a test that is sensitive enough to identify them. Seven out of ten. And with gluten sensitivity, auto-immune diseases are ten times more common.ย So most of them die with auto-immunity disease. So, it shortens your life, reduces the quality of your life, you suffer more. But it doesnโt happen in a day with one family. Unfortunately, it happens accumulatively over a number of years.ย
Mark: Now, the last phase of question I was actually givenโฆ I have never heard of this oneโฆ But I wanna ask youโฆ This is what Natalie Path saidโฆ Not sure if this is correct.ย
But she said that, if youโre gluten intolerant, you may not be intolerant to all types. She said there are four types. But I never heard of four types. Have you heard of this, or is it Natalie Path completely no idea what she is talking about?ย
Dr. OโBryan: I donโt know what you are talking about four types of gluten. There are different strains of wheat, there are different peptides when you break the wall. And efficiently, there are different peptidesโฆ 33-mer, 17-mer, 11-merโฆ There are over 60 peptides that are fugitive.ย Meaning start their immune response from gluten. Thereโs different types of gluten. But it seems like this person is talking about different categories of gluten. And I donโt know what she is referring to.ย
For example, letโs talk bout sprouted wheat. And is it better to eat sprouted wheat? The answer is no. The proteins are not broken down into single amino acids. With sprouted wheat, they still have to be digested, and the body is very resistant in digesting this protein. So, vast majority of people will still have gluten sensitivity and celiac disease eating sprouted wheat. You canโt do it, itโs not a safe food.
Mark: Please correct me if I get this wrong. But when we eat gluten, gluten raises antibodies, and those antibodies attack the gut, in turn that inflames the G.I. tract, and that attacks intestinal lining and the cell wall set up to increase gut permeability and all those things that we donโt want. And that can cause leaky gut.ย Is that right, or am I missing something in the picture there?
Dr. OโBryan: That is correct. You got it exactly correct.
Mark: Excellent. So, what are your final thoughts, and how would you sum up gluten?
Dr. OโBryan: One of the 70 pregnant women admitted to the hospital with any reason, whatsoever, turned out to be a celiac patient.ย Now to be a celiac patient, you have to have a total villous atrophy. So if they have expanded their horizons, to look for total villous atrophy, or just an increase of inflammation from gluten, the number wonโt just be one out of 70. It would probably go up to 20 or 30 out of 70 who have gluten sensitivity. But the only numbers they used were the celiac. So itโs one out of 70 having celiac disease.ย
Ninety percent of these women have poor outcome of pregnancyโฆ 90% of them. Meaning, they lost the baby, it was a premature birth, and the baby was born with birth defect something 90% of them. Everyone of those women, when you put tem on a gluten-free diet for a year, nine out of them had a healthy second baby. No Iโm sorry, eight out of nine of them had a healthy second baby.ย
This kills people. It kills people and you donโt know that it was gluten.ย You think that it was an unexplained miscarriage.ย You think that it was liver problems, that you got the mother died with. No, it was liver problem secondary to gluten sensitivity.ย You think it was heart attack your grandfather died with. No, it was heart attack secondary to gluten sensitivity. Much of the time. Much of the time.
So if you donโt feel like a million bucks in life, the first thing, the very first thing I would recommend people to considerโฆ If you donโt feel like a million bucks โฆ and that means not artificially, with 2, 3, 4 cups of coffee a day, or couple of pasta in the afternoon to keep your energy up or eating lots of candy, or excess exercise, nothing to keep you artificially stimulated. If you donโt feel like a million buck, please consider gluten as a potential candidate thatโs holding you back from living the life that you deserve to live.ย
Mark: Yeah, yeah, for sure. So, you have a couple of dvdโs and Iโm sure there are a lot of listeners out there who wanna learn more about gluten. Can you direct us on how we can get hold of those dvdโs and podcasts and things that youโve done.
Dr. OโBryan: Yes, of course. My website is www.thedr.com and thereโs a link to a number of past webinars and interviews that Iโve done. You can listen to them.
ย And there are two dvdโs. The first dvd is about two and a half hours. Itโs with my friend Susan Vess, and a brilliant nutritionist, and a cook, a chef. Her website is specialeats.com. And that dvd, I talked for two and a half hour to the general public, with slides, pictures, and presentation on what is gluten sensitivity, what is celiac disease, how can I manifest, and I do that for two and a half hours. And Susan comes on and discuss about how to begin a gluten-free diet. And thatโs on the website, thedr.com.
The second video is a set, itโs a 3-dvd set. A professional video of my all-day talks last year on gluten for doctors. So itโs a little more technical, much more technical.ย But that one, if doctors order that, or help your practitioners order that… they take a test, we then list them on the website as a gluten coach.ย And we put a caddy out there, which says, โI donโt know how these people practice, but they were on the seminar, or they reviewed the seminar and passed the test. So they know about gluten.โ
And so thatโs called โfind a gluten coach.โ Itโs on our website also. Doctors order that second DVD, they take a test, they then become a gluten coach. Thereโs no charge for them for that, no back end, I donโt want anything from them. I just want people to be able to find somebody that knows what they are talking about when theyโre dealing with gluten sensitivity.ย
So two DVDโsโฆ The two and a half hour one and the seminar one. Theyโre both on the website.ย
Mark: Excellent. And what does the future hold?
Dr. OโBryan: Gluten sensitivity, the mechanism, the most common mechanism that stimulates the development of autoimmune diseases.ย And the papers will be coming out on that in the next two to three years. Paper after paper after paper. ย
Tests are about to be available called predictive antibodies. Where you can do a panel of 24 antibodies, usually antibodies is $200-$300 for one, and this lab is doing us 24 antibodies for about $400., I think. So itโs gonna be 24 different antibodies to your brain. And you can find where the autoimmune mechanism is going on to your brain, years before thereโs so much damage, when thereโs an obvious symptomโฆ. or antibodies to your heart, or antibodies to your skin, or antibodies to lupus. Years before you have symptoms. Which will give the patients an opportunity, a window of opportunities to shift their lifestyle. Because they will be able to show you whatโs coming down the pipe for you.ย
So thatโs on the horizon. Our goal right now is to get a word of about gluten completely. So that every doctor know just the basics about this. And then educate how to address gluten sensitivity and the celiac disease.
Mark: Sounds fantastic. Youโre really doing some awesome work. And I want to thank you so much for being on the show. And just reminding our listeners to check out Dr. Tom OโBryan sโ website: www.thedr.com, for more in formation, you have to contact Dr. OโBryan.
So thanks once again. Really appreciate it. Wish you the best of luck in the future. Thank you so much for your contribution in the field of nutrition because itโs absolutely awesome.ย
Dr. OโBryan: Thank you so much. And thank you for spreading the word with us out there. And the people that listen to you todayโฆ this may change their life.ย So thank you so much for this opportunity to share this information.ย
Mark: Youโre very welcome. Speak to you next time Tom.
Dr. OโBryan: You bet, bye-bye.
Mark: So that was the gluten show. Hope you enjoyed. Remember to check out Dr. Tom OโBryanโs dvdโs at www.thedr.com. Links can be found in my website, or just jot in to Google to find this out.ย
Hope you guys enjoyed. Post your comments and remember to share this with your loved ones and your friends. Speak to you next time guys!

